Using COADREAD, luteolin, and COADR as keywords, the signaling pathways were searched in databases, including the Comparative Toxicogenomics Database (CTD, http://ctdbase.org/) and STITCH (http://stitch.embl.de/) and MalaCards (https://www.malacards.org/) databases. The Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses were conducted using the R package ‘ggplot2’.
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