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JW Junqing Wang
YT Yuan Tian
YS Yi Shao
HF Hui Feng
LQ Limin Qin
WX Weiwei Xu
HL Hongjuan Liu
QX Quangang Xu
SW Shihui Wei
LM Lin Ma
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For the cumulative clinical measurements, chi-square test was used for gender and optic neuritis episode comparisons. Then, independent sample t-test was used for duration of NMO-ON or ON and time since last relapse comparisons. One-way analysis of variance (ANOVA) with Bonferroni post hoc test was used for age and Expanded Disability Status Scale (EDSS) comparisons using SPSS version 16.0 (SPSS Inc., Chicago, IL, USA).

A one-way ANOVA was used to identify regions in which the spontaneous activity pattern was different between the AQP4-IgG+NMO-ON and MOG-IgG+ON groups and HCs. We performed post hoc analysis tests after regressing out age and gender effects to compare the ReHo values between each pair of groups (P<0.01, cluster >40 voxels, and AlphaSim corrected).

The relationship between the mean ReHo value of NMO subjects and the clinical features was analyzed by a Pearson correlation analysis using SPSS version 16.0 (P<0.05 was considered to be a significant difference).

Copyright and License information:  ©2017 Wang et al. This work is published and licensed by Dove Medical Press Limited
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