Improve Research Reproducibility A Bio-protocol resource
Concise Method
tooltip

Patient Recruitment

YZ Yi Zhai
JL Jinyu Li
WY Wangshu Yu
SZ Sha Zhu
YY Yinhui Yu
MW Menghan Wu
GS Guizhen Sun
XG Xiaohua Gong
KY Ke Yao
request Request a Protocol
ask Ask a question
Favorite

The research protocols of this study adhered to the guidelines of the Declaration of Helsinki and were approved by the Medical Ethics Committees of the Second Affiliated Hospital, College of Medicine, Zhejiang University (Hangzhou, China). Appropriate informed consent from each participant was obtained.

Among 27 families, 24 were diagnosed with congenital cataracts, while 3 were diagnosed with aniridia and congenital cataract. 25 families with family history showed autosomal dominant inheritance, and 2 were sporadic patients. Available individuals indicated in Fig. 1 were given complete physical, ophthalmic examinations. One hundred unrelated healthy subjects from the same ethnic background were recruited as controls. Peripheral blood was collected by venipuncture in EDTA-coated Vacutainer tubes (BD, New Jersey, USA) and stored at −20 °C.

Copyright and License information: The Author(s) ©2017
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

post Post a Question
0 Q&A