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The H/M ratios of 123I-MIBG myocardial scintigraphy have an estimated specificity of ≥0.90 according to previous studies.12-16 Furthermore, diagnostic biomarkers for LBDs require a specificity of ≥0.80.4 A sample size of 26 patients with non-LBD produces a 2-sided 95% CI with a width equal to 0.15 when the sample specificity is assumed to be ≥0.90.
Copyright and License information: ©2022 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.
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