Estimation of the Abundance of Immune Cell Populations

FC Fangru Chen
JM Jian Meng
WY Wenjie Yan
MW Mengjiao Wang
YJ Yunfei Jiang
JG Jintao Gao
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The cell-type identification by estimating relative subsets of RNA transcript (CIBERSORT) deconvolution algorithm (Newman et al., 2015) was adopted for computing the enrichment of infiltrating immune cell populations following the gene sets of diverse immune cell types. The degree of immune cell infiltrations was inferred utilizing the CIBERSORT package with LM22 the reference set. This analysis was implemented with 1,000 simulations as well as the results were filtered with p < 0.05.

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