In all experiments, data were analyzed using SPSS software v.21.0 (SPSS Inc., Chicago, IL, USA). Student's t-test was performed for statistical analysis. For abnormal spindle and chromosome alignment, chi-square test was performed for statistical analysis. Unless otherwise stated, * = P < 0.05, ** = P < 0.01, *** = P < 0.001, ns = non-significant difference (P > 0.05).
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