The clinical and pathological variables of the enrolled patients were retrospectively collected from the database, including: age, gender, body mass index (BMI), hypertension, hyperglycemia, hypertriglyceridemia, high-density lipoprotein cholesterol (HDL-C), current smoking, hemoglobin (Hg), pathologic tumor stage (pT), lymph node status (pN), pathologic grade, concomitant carcinoma in situ (CIS), variation and adjuvant therapy. All surgical specimens after RC were processed according to standard pathological procedures. Genitourinary pathologists assigned tumor pathologic grade and clinical stage according to the 2004 WHO/International Society of Urologic Pathologists classification of bladder urothelial cancer and the 2017 TNM staging system of the AJCC, respectively.
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