Cohort 1 (the Clinical Research Center Project of Shanghai Mental Health Center)

WL Wei Li
LY Ling Yue
LS Lin Sun
SX Shifu Xiao
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Cohort 1 was derived from the CRC2017ZD02 program and consisted of 476 elderly people, including 135 amnestic mild cognitive impairment (aMCI) patients, 22 AD patients, and 319 normal controls. This cross-sectional study was conducted in Shanghai (China) between 2013 and 2015, and all the subjects were elderly people in the community who were not taking cognitive drugs. By using standardized questionnaires, we collected their general demographic information (such as age, gender, education, BMI), daily living information (such as smoking, drinking, drinking tea, hobbies and exercise) and disease related information (such as hypertension, diabetes, hyperlipidemia and heart disease). In addition, we also measured their liver metabolism related indicators, such as AST, ALT, high density lipoprotein, low density lipoprotein, fasting blood glucose, triglyceride, cholesterol and APOE E4.

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