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Mice were housed individually under standard laboratory conditions (1212 h light/dark cycle, lights on at 0600 h) with a room temperature of 21°C. Water and food were available ad libitum unless otherwise indicated. EVs were extracted from either male or female 6month-old wild type (C57BL/6 background) or heterozygous CTR (HetCTR) mice (same background as wild type). HetCTR mice generated breeding pairs obtained from Drs. R.A. Davey and JD Zajac and have been shown to express 50% reduction of CTR [18, 23]. For in vitro LTP experiments, we used FVB strain of mice.
Copyright and License information: ©2022 Soudy et al
This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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