The cost of overage must take into account depreciation expense, as wear and tear occurs every time an instrument is used and reprocessed. The formula to represent this is Cdepreciation = Cinstrument purchase ÷ Ndesignated uses. The device procurement office provided the researchers with the instrument purchase cost (Cinstrument purchase) as well as the maximum number of uses recommended by the manufacturer (Ndesignated uses), which was used as a proxy for the lifespan of the instrument.
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