2.6.4. Region of interest analysis

YC Ying‐Chun Chen
YH Yun‐Hsin Huang
NY Nai‐Shing Yen
request Request a Protocol
ask Ask a question
Favorite

We selected the aMCC, mPFC, and NAcc as a priori regions of interest (ROIs) based on previous studies that linked responses in these regions to self‐reward and other‐reward (Apps & Ramnani, 2014; Enzi et al., 2009; Knutson et al., 2005; Lockwood et al., 2018; Moran et al., 2006). We built spheres with a radius of 5 mm centered at the coordinates of the vaMCC ([4, 24, 24] Enzi et al., 2009), daMCC ([−3, 19, 38] Moran et al., 2006), mPFC ([−3, 47, 0] Moran et al., 2006), and NAcc ([−11, 11, −4] and [12, 14, −4] Knutson et al., 2005) based on literature evidence using the MarsBaR 0.44 (Brett, Anton, Valabregue, & Poline, 2002). Greater neural activity in these regions was correlated with behavioral indices using bivariate correlations. The α value was set at 0.007 using Bonferroni correction (i.e., 0.05/7 ≈ 0.007) to correct for multiple comparisons (seven subscales).

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

post Post a Question
0 Q&A