Surrogate Neutralization Assay

LG Louis Grandjean
AS Anja Saso
AO Arturo Torres Ortiz
TL Tanya Lam
JH James Hatcher
RT Rosie Thistlethwayte
MH Mark Harris
TB Timothy Best
MJ Marina Johnson
HW Helen Wagstaffe
ER Elizabeth Ralph
AM Annabelle Mai
CC Caroline Colijn
JB Judith Breuer
MB Matthew Buckland
KG Kimberly Gilmour
DG David Goldblatt
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A 96-well custom competition assay, designed to measure the inhibition of ACE-2 receptor binding to S protein or RBD by serum-derived antibody (MSD), was performed on 94 serial samples from 46 participants (2 participants had 3 serial samples) to establish in vitro correlates of functional immunity.

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