MGCD was kindly provided by ROCHE R & D CENTER (CHINA) LTD. Nutlin-3 was purchased from Sigma. For western blot detection, we used Ac-Histone H3 (Upstate), Histone H3, Cleaved caspase-3, Bcl-2, Cyclin B1, Bax (Epitomics), p-cdc2 (Tyr15), cdc2, p53, p21 (Cell Signaling Technology), cleaved PARP (Santa Cruz), and GAPDH, tubulin (Proteintech Group) antibodies.
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