Maintenance of animals and generation of carcinogen- and HBV-related HCC mouse models

HL Hsueh-Chou Lai
CY Chun-Chieh Yeh
LJ Long-Bin Jeng
SH Shang-Fen Huang
PL Pei-Ying Liao
FL Fu-Ju Lei
WC Wei-Chun Cheng
CH Cheng-Lung Hsu
XC Xiujun Cai
CC Chawnshang Chang
WM Wen-Lung Ma
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All of the animal experiments followed the Guidelines for the Care and Use of Laboratory Animals (Ministry Of Sciences and Technology, Taiwan) and were approved by the China Medical University Committee of Laboratory Animal Welfare (101-38-N). Liver-specific ARKO (LARKO) and HBVtg-LARKO mice as well as the spontaneous HCC mouse model were generated using previously described protocols [3, 4].

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