Improve Research Reproducibility A Bio-protocol resource
Concise Method
tooltip

Tumor Immune Dysfunction and Exclusion (TIDE) Analysis

KZ Kai Zhang
YQ Ying Qian
XQ Xiaowei Quan
TZ Tengteng Zhu
BQ Biyun Qian
request Request a Protocol
ask Ask a question
Favorite

TIDE is an effective algorithm that integrates two mechanisms of tumor immune escape—T-cell dysfunction and T-cell exclusion, which could be useful to predict immune checkpoint inhibitor (ICI) response in cancer treatment. The TIDE online web (http://tide.dfci.harvard.edu) was used to calculate the TIDE score, MSI score, T-cell exclusion score, and T-cell dysfunction score with the normalized RNA-seq data.

Copyright and License information:  ©2022 Zhang, Qian, Quan, Zhu and Qian.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

Do you have any questions about this protocol?

Post your question to gather feedback from the community. We will also invite the authors of this article to respond.

post Post a Question
0 Q&A