The chi-square test, Student’s t-test, and Wilcoxon rank-sum test were used to compare the differences between variables for patients with and without prehospital notification. The PPV, sensitivity of prenotification, and 95 % confidence intervals (CIs) were calculated. Spearman's rank correlation coefficient was used to evaluate the association between median DTN time and the volume of patients receiving thrombolytic therapy in individual hospitals. SAS software (Version 9.2, SAS Institute Inc., Cary, NC) was used for statistical analyses. A two-tailed p-value less than 0.05 was defined as statistically significant.
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