Study population

Thirty-three patients with febrile seizures were recruited [Simple FS-19; Complex FS-14]. Confirmation of the diagnosis of febrile seizures was based on clinical parameters and biochemical investigations according to the American Academy of Pediatrics guidelines¹. After the exclusion of subjects with uncorrectable head motion, 24 subjects were included in the final analysis [Simple FS-11 and Complex FS-13]. The Male: Female ratio was 10:3 and 8:3 in the CFS and SFS groups respectively (p = 1.0). A positive family history of seizures was present in four and three patients in the CFS and SFS groups respectively. Time interval from the last seizure to the MR imaging for the CFS and SFS groups were 12 days [IQR = 8.5–13.5] and 10 days [IQR = 9–30] respectively. Among the clinical variables analysed viz mean age at onset, the number of recurrent febrile seizures, the maximum duration of febrile seizures, duration of the disease, none showed significant between-group differences.

The demographic and clinical features of the patients are provided in Table ​Table33.

Demographic and clinical features of the patients.

n number of subjects, m months, d days, min minutes, SD standard deviation, IQR inter quartile range.