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For the statistical analysis, SPSS 26.0 (Statistical Package for the Social Science, SPSS Inc., Chicago, IL, USA) software was used and figures were created using GraphPad Prism 5. Experimental data were presented as mean ± SD. Mann–Whitney tests were used for ordinal/semiquantitative variables, Fisher tests for qualitative variables and one-way ANOVA was used for multi-group comparisons. For quantitative variables, data comparison used Student’s t-tests. A value of p < 0.05 was considered statistically significant.
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