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To predict the immunotherapy sensitivity, the Immunophenoscore (IPS) was calculated using the Cancer Immunome Atlas (https://tcia.at/). The IC50 of common chemotherapeutic drugs was counted in the training group via the administered “pRRophetic” package to evaluate the predictive capability of the GARS for drug therapeutic responses. The Wilcoxon rank test was then used to compare the difference in IC50 between the low and high GARS groups. Finally, we applied the “ggplot” R package to paint the result in the histogram.
Copyright and License information: ©2022 Jiang, Ouyang, Zhang, Yu and Yao.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
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