RESOURCE AVAILABILITY

Further information and requests for resources and reagents should be directed to and will be fulfilled by the lead contact Laura Baranello (laura.baranello@ki.se).

The material generated in this study is available upon request from the lead contact.

The deep sequencing data reported in this paper were deposited in the GEO database and are publicly available as of the date of publication. Previously published RNA-seq data, RNAPII and MYC ChIP-seq data from HCT116 and U2OS cells (Lorenzin et al., 2016; Baranello et al., 2016; Ibarra et al., 2016) are publicly available in GEO. Accession numbers of all aforementioned datasets are listed in the Key resource table.

This paper does not report original code since it is based on implementation of publicly available software. Published software and code used in this study are listed in the Key resource table. Any additional information required to reanalyze the data reported in this paper is available from the lead contacts upon request.