Study setting

CF Carole Fogg
SF Simon D. S. Fraser
PR Paul Roderick
SL Simon de Lusignan
AC Andrew Clegg
SB Sally Brailsford
AB Abigail Barkham
HP Harnish P. Patel
VW Vivienne Windle
SH Scott Harris
SZ Shihua Zhu
TE Tracey England
DE Dave Evenden
FL Francesca Lambert
BW Bronagh Walsh
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The UK has a registration-based primary healthcare system where patients are registered with a single general practice. Patients are allocated a personal lifetime unique identifier, (a National Health Service (NHS) number), which reduces the risk of duplicate records and facilitates the linkage of primary care to other healthcare datasets. The Oxford-Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) is a network of around 5% of primary care practices in England which contribute electronic health record data voluntarily. Practices registered with the RCGP RSC have been shown to be nationally representative in terms of the population served and health outcomes [19, 20].

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