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Study design and sample

NW Ningjian Wang
YS Ying Sun
HZ Haojie Zhang
CC Chi Chen
YW Yuying Wang
JZ Jihui Zhang
FX Fangzhen Xia
CB Christian Benedict
XT Xiao Tan
YL Yingli Lu
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The UKB is a prospective cohort study that included more than 500 000 community‐dwelling adults aged 40–69 years across the United Kingdom between 2006 and 2010 (https://www.ukbiobank.ac.uk/). Detailed information about the UKB has been provided in a previous study. 15 We declare that all data are publicly available in the UKB repository. 15 The North West Multi‐Center Research Ethics Committee Study approved the UKB study, and all participants provided written informed consent.

A total of 502 505 participants were recruited. We excluded those with missing values on body composition parameters (fat mass and muscle mass in arm, leg, trunk, and whole body) (n = 11 443) and those with diabetes at baseline (n = 27 397). The final sample was 464 817 (207 286 men and 257 531 women).

Copyright and License information:  ©2021 The Authors. Journal of Cachexia, Sarcopenia and Muscle published by John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders.
This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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