2.6. Salivary IgA Measurements

MR Marcella Reale
CU Claudio Ucciferri
EC Erica Costantini
MN Marta Di Nicola
AP Annamaria Porreca
PG Pamela Di Giovanni
MP Michela Pontolillo
AA Antonio Auricchio
JV Jacopo Vecchiet
KF Katia Falasca
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Secretory IgA concentrations were determined to evaluate the local immunity status in different disease conditions, including respiratory diseases such as pneumococcal disease. The two-site sandwich enzyme immunoassay for secretory IgA was purchased from Bio Vendor Research and Diagnostic Products (Brno, Czech Republic), with a sensitivity assessed as 0.6 µg/mL. The lower detection limit was 57 µg/mL for saliva samples, and the upper limit was fixed at 260 µL/mL.

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