All data are expressed as mean +/− SEM. Comparisons between groups were assessed for significance by two-way analysis of variance (ANOVA) or T-test after assessment of normality of distribution. Logarithmic transformation was performed of data that had non-normal distribution to meet requirements of ANOVA analysis. The conclusions drawn after data transformation remain valid for the original data. If significance was established, posthoc analysis was done using Tukey’s test. A value of p < 0.05 was considered statistically significant.
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