Values of pain tests represent the average of three trials at each time interval and plotted as time latency versus duration of test. For the immunoassays, the measured levels of each cytokine were averaged on every tissue removal date for each experimental group. Comparison among groups was located using a one-way ANOVA followed by a Bonferoni post hoc test. Results having p < 0.05, p < 0.01, and p < 0.001 were considered significant.
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