2.1. Assessment of Diabetic Neuropathy (DN)

In the SNDREAMS study, DN assessment was done on all participants with diabetes by measuring VPT using a biothesiometer (Kodys, Chennai, India). The VPT was measured by a single observer by placing the biothesiometer probe perpendicular to the distal plantar surface of the great toe of both legs. The VPT was measured at a voltage level when the patient felt the first vibration sensation. The mean VPT measure of three readings of both legs was considered for the analysis. The diagnosis of DN was made if the VPT value was ≥20 V6.