The three‐dimensional mutant S230I protein structure was modeled by the Swiss‐Model program 21 using the hβc receptor wild‐type (WT) structure (PDB: 1GH7). 22 Hydrophobicity surfaces on modeled protein structure were presented by Chimera. 23 The GM‐CSF/GMRα/hβc ternary complex (PDB: 4NKQ) 24 was used for superimposition analysis.
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