MRI acquisition

MRI scanning was performed on a 3.0 T MRI scanner (Ingenia, Philips Medical Systems, the Netherlands) with an 8-channel receiver array headcoil. High-resolution T1-weighted axial images covering the whole brain were obtained by a 3D magnetization prepared rapid gradient-echo sequence: TR = 8.1 ms; FA = 90°; TE = 3.7 ms; FOV =240 × 240 mm; acquisition matrix = 240 × 222; gap = 0 mm, thickness = 1.0 mm; number of slices = 170. T2-weighted images were acquired using the following parameters: TR = 4000 ms; TE =107 ms; FA = 90°; FOV =230 × 230 mm acquisition matrix = 384 × 384; thickness = 1.5 mm; gap = 0 mm, number of slices = 18. DWI-weighted images were obtained with the following: TR = 2503 ms; TE =98 ms; FA =90°; FOV =230 × 230 mm acquisition matrix =152 × 122; thickness = 1.5 mm; gap = 0 mm, number of slices = 18. Susceptibility weighted imaging (SWI)-weighted images were acquired using the following parameters: TR = 16 ms; TE =23 ms; FA =10°; FOV =220 × 180 mm; acquisition matrix = 220 × 180; thickness = − 0.6 mm; gap = 0 mm, number of slices = 200. Additionally, T2 fluid-attenuated inversion recovery (FLAIR) axial images were obtained with the following parameters: TR = 10,000 ms; TE = 120 ms; FA =110°; FOV =220× 220 mm; acquisition matrix = 336 × 189; thickness = 1.5 mm; gap = 0 mm, number of slices =18 [24].