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Trial sequential analysis

ZW Zhiyu Wang
YW Yaning Wei
LA Lin An
CX Chenglin Xi
KW Kunjie Wang
DH Dan Hong
YS Yan Shi
AZ Aiming Zang
SS Shenyong Su
WL Wenwen Li
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Trial sequential analysis (TSA) was performed using TSA software, version 0.9.5.10 (https://ctu.dk/tsa/), with the following parameters: type I error (5%), 95% CI, relative risk reduction (20%), and type II error (20%). Evidence was confirmed as reliable if the cumulative Z-curve surpassed the required information size (RIS) line or passed through the sequential monitoring boundary of the trial; otherwise, more articles were deemed to be required. 16

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Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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