Participants indicated in a daily evening diary questionnaire whether they smoked that day or not by answering the question, “Did you smoke today (including only one puff)?” (coded as 0=yes and 1=no) [36,37]. To objectively assess smoking abstinence, participants were instructed each evening to assess exhaled CO with their personal iCO Smokerlyzer. The iCO Smokerlyzer is a CO-monitoring device that is used with a corresponding Smokerlyzer app [33]. At the end of the end-of-day diary questionnaire, participants were instructed to take a CO measurement with their personal iCO Smokerlyzer and the corresponding app. The Smokerlyzer app displayed the test values in parts per million (ppm) and automatically generated a result report. Participants were instructed to send their result report directly from the app via email to the study team and to report the ppm value in the end-of-day diary. The iCO Smokerlyzer test values were categorized as 1 for abstinent (0-6 ppm) and as 0 for not abstinent (>6 ppm) [33,38]. A recent study points to comparable results between the iCO Smokerlyzer and the more studied piCO+ Smokerlyzer, which has been shown to validly distinguish between smokers and nonsmokers [38,39].
If participants answered the smoking abstinence measure with yes (=today smoked), they were asked to report the number of cigarettes they had smoked that day. Otherwise, the daily number of cigarettes smoked was coded as 0 [37].
The daily use of nicotine replacement products (NRPs) and a variable denoting whether days were weekdays or weekends were included as covariates in the sensitivity analyses. Research shows that using NRPs increases the probability of smoking cessation success [40], and smoking behavior has been shown to differ during weekends [41], which might be related to trigger exposure. NRPs were not provided to participants; however, the SmokeFree buddy app (ie, the knowledge base feature) incorporated encouragement to use NRPs for smoking cessation. Participants indicated in the daily diary whether they used NRPs or not by answering the question “Did you use nicotine replacement products today (eg, nicotine gum, nicotine patch, medications as for example Champix, etc)?” (0=no and 1=yes). Furthermore, with each timestamp of the daily diary, a variable was calculated, whether it was a weekend or not (0=no weekend and 1=weekend).
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