The formation of k-spaced amino acid pairs encoding technique12,21,35 calculates the occurrence frequencies of the pairs of k-spaced amino acids from a segmented protein sample, that can express the short linear motif information out of it12,30. For instance, the encoding of a peptide segment will be a 441-dimensional feature vector if . This can be defined as,
where n stands for any of amino acid, means the occurrence frequency of all k-spaced amino acid pairs35 and means the occurrence frequency of the AnA pairs in the segment20 when . In this study, after merging each of the 441-dimension feature vectors for , a total of 2205-dimensional features have been formed.
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