The recommendations of radiation oncology working group (RTOG) 90-05 (17) suggest that the SRS dose of brain metastases should be determined according to the size of lesions, varied from 15 to 24 Gy, and the prescribed dose should be 24 Gy for tumors <2 cm in maximum diameter. Therefore, the target dose of all cases in this study was 24 Gy delivered through one fraction. The constraints of OARs included optic nerve and chiasm maximum dose of 10 Gy and brainstem maximum dose of 12 Gy.
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