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We conducted the mouse model of cardiac hypertrophy induced by Ang II infusion as previously described (16). Ang II (1.4 mgkg−1 per day and dissolved in 0.9% NaCl) was subcutaneously infused for 4 weeks using an osmotic minipump (Alzet model 2004, Alza Corp) implanted into each mouse. The control mice group were received the same procedures as the experimental animals, with the same dose of saline infusion.
Copyright and License information: ©2021 Pang, Ma, Wang, Li and Jiang.
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