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JI Joshua Iruedo
DO Don O’Mahony
SM Sikhumbuzo Mabunda
GW Graham Wright
BC Busisiwe Cawe
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The study population was all patients who were started on MDR-TB treatment from January 2009 to December 2014 in KSD. All patients were admitted and initiated on MDR-TB treatment in a designated TB hospital. As it was not possible to ensure that all patients with MDR-TB in KSD were identified through a review of medical records, a sample size was calculated to ensure that the number identified was sufficient for analysis.

South Africa had a MDR-TB prevalence of 5.9% (p = the anticipated population proportion) in 2014. Using the 95% confidence interval (z = 1.96) and a precision (d) of 3%, the minimum sample size (n) was calculated using the following equation [26]: n = p(100-p)z2/d2. The minimum sample size was 237 and a further 20% (~48) was added to account for lost-to-follow up or data entry errors [27]. This yielded a sample size of 285 subjects using a purposive sampling method.

Copyright and License information: The Author(s). ©2017
Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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