The Gene Expression Omnibus (GEO, http://www.ncbi.nlm.nih.gov/geo/) database was retrieved in order to obtain the microarray data of lung SCC (up to January 1, 2015). The datasets including more than six lung SCC cases or controls. The inclusion criteria of datasets were set as follows: 1) the whole-genome expression profiling of lung SCC tissues or normal control tissues was available in the datasets; and 2) patients did not have preoperative treatment before collection of tumor tissues and normal controls. A total of six mRNA expression datasets of lung SCC were used in our study. Two datasets were based on a platform of GPL6480 Agilent-014850 Whole Human Genome Microarray 4x44K; other datasets were based on platforms of GPL10558 Illumina HumanHT-12 V4.0 expression beadchip, GPL6947 Illumina HumanHT-12 V3.0 expression beadchip, GPL9053 Agilent-UNC-custom-4X44K, and GPL570 [HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array.
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