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Data Analysis and Statistics

JJ Jae Hun Jung
YJ Yong Woo Ji
HH Ho Sik Hwang
JO Jae Won Oh
HK Hyun Chang Kim
HL Hyung Keun Lee
KK Kwang Pyo Kim
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The areas were extracted using Skyline 3.7ver52. Savitzky−Golay smoothing was applied to increase the quality of the chromatograms. Peptides’ areas between 204 runs were normalized to ß-galactose peptide (APLDNDIGVSEATR, 729.36 m/z (Q1) → 563.28 m/z (Q3), CV = 16.58%) to correct experimental variation. The best transition was selected on the basis of intensity and consistency for the quantification. Independent t-test, ROC (receiver operating characteristic) analysis was conducted using SPSS version 21.0 (IBM Corp., Armonk, NY, USA) to determine the significance of target proteins.

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