All data were analyzed using Prism 6 software (GraphPad Software Inc., La Jolla, CA, USA), and differences between the groups were analyzed using the Mann–Whitney U test, the Kruskal-Wallis test followed by Dunn’s multiple comparisons test, or the Wilcoxon rank-sum test. The significance level was set at p < 0.05. Associations between two variables were analyzed using Spearman’s correlation.
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