HLA Genotyping.

BA Burcu Ayoglu
NM Nicholas Mitsios
IK Ingrid Kockum
MK Mohsen Khademi
AZ Arash Zandian
RS Ronald Sjöberg
BF Björn Forsström
JB Johan Bredenberg
IB Izaura Lima Bomfim
EH Erik Holmgren
HG Hans Grönlund
AG André Ortlieb Guerreiro-Cacais
NA Nada Abdelmagid
MU Mathias Uhlén
TW Tim Waterboer
LA Lars Alfredsson
JM Jan Mulder
JS Jochen M. Schwenk
TO Tomas Olsson
PN Peter Nilsson
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Allelic dosage of HLA-DRB1*15 and HLA-A*02 were obtained by imputation of HLA types from SNP genotypes in the MHC region using the HLA*IMP:02 program (34). The genotypes were generated using the Illumina Human Quad 660 chip, the Immunochip custom array, or both. Genotyping was carried out in previous studies analyzing the genetic risk of MS for the individuals included in this study (35, 36). Only HLA genotypes with a quality score above 0.7 were included.

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