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Selection of DEGs (in IGA) and signatures (in GSA) for clustering
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In IGA, datasets are represented by log2-ratios of 152 genes with the highest variance across datasets. In GSA, datasets are represented by NESs of the most significantly enriched/depleted signatures (in GSEA, 152 signatures determined by those having a nominal p-value < 0.05 in not less than 10 of the 18 datasets; in PAGE, 148 signatures determined by FDR <5e-21; in GAGE, 167 signatures determined by FDR <5e-08).
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