All chemicals were purchased from Sigma. Microwave-assisted reactions were performed in a single mode CEM apparatus; High Resolution Mass Spectrometry (HRMS) Spectra were determined on a MSQ Orbitrap Thermofinnigan spectrometer and Nuclear magnetic resonance (NMR) spectra on a Brucker Avance 600 spectrometer (600 MHz). 6BIO was synthesised as previously described34 and analytical data (HRMS and NMR) were conformed to literature. Purification of the synthesised product was conducted using flash silica gel 60 (40–63 μm) from Merck; the purity of the synthesised compound has been determined by High-performance liquid chromatography (HPLC) and was above 95%.
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