Adherence to oral endocrine treatment

AV Antonis Valachis
HG Hans Garmo
JW John Weinman
IF Irma Fredriksson
JA Johan Ahlgren
MS Malin Sund
LH Lars Holmberg
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Adherence to oral endocrine therapy was investigated during the first 2 years after breast cancer diagnosis after a run-in period of 6 months to minimize the risk for overestimation of non-adherence due to patients that were treated with chemotherapy after breast cancer diagnosis.

Patterns of adherence were assessed based on tamoxifen and AI-dispensed prescriptions recorded in the Swedish Prescribed Drug Register. Adherence to oral endocrine treatment was measured by calculating the medication possession ratio (MPR) [21, 22]. MPR is defined as number of days of dispensed prescribed supplies divided by the number of days in study period × 100 %. Actual prescribed daily dose (PDD) for each patient was used for the MPR calculations.

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