The Pain Impact Score (PIS) is calculated from the PROMIS-29 pain intensity, physical function, and pain interference subdomains. The raw scores of these measures are combined to define a single digit score. The raw score for physical function is inverted so that higher raw scores denote worse function. The raw score ranges from 0 to 10 for pain intensity and 4 to 20 for pain interference and physical function. The PIS ranges from 8-No Impact (pain intensity of 0, pain interference of 4, physical function of 4) to 50-High Impact (pain intensity of 10, pain interference of 20, physical function of 20).7
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