Based on our previous study on general population of Mashhad aged 15-65 years, we had 815 cases of age-, and sex-matched to our patients with CD with negative tTG who were selected as control group. Individulas aged less than 18 years and more than 60 years were excluded. After applying inclusion and exclusion criteria finally 657 (3 times of patients with CD group) cases for control group were selected randomly. Patients with confirmed CD were selected by means of purposive sampling.
Of the 301 patients with CD, we also excluded patients aged less than 18 and more than 60 years. In the celiac group 48 patients aged less than 18 years, 3 patients aged over 60 years, 17 patients with tTG titer below 30 (UN/mL), or with missed data, and 14 patients with Marsh=<1 were excluded. Finally 219 patients in celiac group were included in this study. The results are shown in tables 1 and and22.
So, the study was conducted on two groups with confirmed CD (case group) and the healthy population (control group).
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