2.6. Ciliary gene set

The list of ciliary genes was derived by combining: (i) SYSCILIA gold standard cilia gene list (303 genes) [21] and (ii) genes with the annotation “cilium” in the GO human database, searched for using AmiGO (791 genes) [22]. The resulting list contained 864 genes involved in ciliary functions with gene products localized within and/or outside the ciliary compartment (Supplementary Materials, Table S1). One-tailed hypergeometric test was performed to evaluate any over-representation of ciliary genes in the set of liver-expressed genes.