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2.3. Assessment of Response to Therapy

YA Yuwa Ando
TK Tomokazu Kawaoka
MK Masanari Kosaka
YS Yuki Shirane
YJ Yusuke Johira
RM Ryoichi Miura
SM Serami Murakami
SY Shigeki Yano
KA Kei Amioka
KN Kensuke Naruto
YK Yumi Kosaka
SU Shinsuke Uchikawa
KK Kenichiro Kodama
HF Hatsue Fujino
TN Takashi Nakahara
AO Atsushi Ono
EM Eisuke Murakami
MY Masami Yamauchi
WO Wataru Okamoto
ST Shoichi Takahashi
MI Michio Imamura
KC Kazuaki Chayama
HA Hiroshi Aikata
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Imaging evaluation was performed according to the Response Evaluation Criteria in the Solid Tumors (RECIST) guidelines [9] and modified RECIST (mRECIST) guidelines [10] with computed tomography and magnetic resonance imaging 6 weeks after the start of treatment. Serum α-fetoprotein (AFP) and des-γ-carboxyprothrombin (DCP) levels were measured 3 and 6 weeks after the start of treatment.

The AFP ratio was calculated using the following equations: AFP ratio at 3 weeks = (AFP value at 3 weeks)/(AFP value before treatment), and AFP ratio at 6 weeks = (AFP value at 6 weeks)/(AFP value before treatment). The DCP ratio was similarly calculated. When the tumor markers remained in the normal range before treatment, at 3 weeks, and 6 weeks, the ratio was calculated as 1.

Copyright and License information:  ©2021 by the authors.
Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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