All analyses were performed using GraphPad Prism Version 9.0.1. (GraphPad Prism Software, La Jolla, CA, USA) and figures were constructed using InkScape Version 0.92.3 (Inkscape Project, open source). Quantitative variables were described as mean values ± 1 standard deviation. PFS and OS were estimated using the Kaplan–Meier method and compared between groups with the log-rank test. Associations between continuous variables were analyzed with a linear regression model and depicted as scatter plots including regression line and R2 value, indicating the coefficient of determination. For all analysis, two-sided p values < 0.05 were considered significant.
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