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Human islets and pancreas tissues

JR Jinxiu Rui
SD Songyan Deng
AP Ana Luisa Perdigoto
GP Gerald Ponath
RK Romy Kursawe
NL Nathan Lawlor
TS Tomokazu Sumida
ML Maya Levine-Ritterman
MS Michael L. Stitzel
DP David Pitt
JL Jun Lu
KH Kevan C. Herold
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Human islet samples were obtained from adult, nondiabetic organ donors from the Prodo Labs (details listed in Supplementary Table 1). Pancreas tissues from donors with autoimmune pancreatitis (n = 5) or chronic pancreatitis (n = 3) were obtained from the Department of Pathology at Yale and histologic slides of the pancreas were obtained from normal individuals (n = 8), nondiabetic donors who were autoantibody+ (n = 7), and C-peptide+ patients with T1D of relatively short duration (n = 7) from nPOD. The use of human tissues and islets was considered “not human subjects research” as per institutional policies (Yale Institutional Review Board). It did not involve data obtained through intervention or interaction with the individual and did not contain identifiable private information.

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