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Gene Set Enrichment Analysis (GSEA)
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GSEA was performed in the TCGA NSCLC cohort using gene sets from Molecular Signature Database (MSigDB) v.7.0 to investigate the biological features of KEAP1/NFE2L2 mutant NSCLC (16). GSEA was conducted by clusterProfilter R package (17). The P-value estimates the statistical significance of the normalized enrichment score (NES). A gene set with P < 0.05 was determined to be significantly enriched in genes.
Copyright and License information: ©2021 Zhu, Xie, Yu, Yao, Xu, Huang, Wu, Li, Zheng, Liu, Xie, Huang, Li, Zheng, Zhang, Qiao, Chan and Zhou
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