An independent examiner will pay another visit to each kindergarten 1 day after the baseline dental examination and fluoride therapy. The presence of any short-term adverse effects in the hard and soft tissues in the oral cavity will be recorded. At the 12-month follow-up, the examiner will determine the presence of any long-term adverse effects. The expected adverse effects include but not limited to gum irritation, gum swelling, gum bleaching and sound tooth surface discolouration. In addition, the investigator’s contact will be left with the parents. If the parents have any concern or notice adverse effects, they can reach the investigators at their own convenience. Follow-ups will be provided on a case-by-case base.
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