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Benzodiazepines included in this study were estazolam, quazepam, triazolam, nitrazepam, nimetazepam, haloxazolam, flunitrazepam, flurazepam, brotizolam, rilmazafone hydrochloride hydrate, lormetazepam and etizolam; non-BZD hypnotic drugs were eszopiclone, zopiclone and zolpidem tartrate; the MRA was ramelteon; and the ORA was suvorexant. Melatonin, an MRA that can be purchased over the counter in other countries, is not approved in Japan.
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